by Laine Bénard, Mikhail Bond, Orchee Haque, Stephanie Huynh and Molly McVean (senior author)
1st Place in the Youreka Canada National Competition
Mutations that alter the amino acid sequence of the SARS-CoV-2 coronavirus spike protein often result in structural changes that affect its transmissibility and infectivity. The objective of this study was to determine whether the presence of the H69del spike protein frameshift mutation is related to the severity of patient outcomes in individuals infected with SARS-CoV-2, as measured by the number of hospitalizations due to COVID-19.